It helps to avoid unnecessary extensive surgery and potential surgery related adverse effects, such as hypothyroidism, hypocalcemia, and recurrent laryngeal nerve injury. Postoperative histopathology was reported as malignant in 58 cases. Hemithyroidectomy is the procedure of choice that should be done for patients that showed benign criteria by FNAB with no abnormality detected by flow cytometric study. This article has been cited by other articles in PMC. Support Center Support Center.

It was transient in nine patients and in four patients it was permanent. Abstract Thyroid nodules are very common in the general population, while thyroid cancer is relatively uncommon. What found in sections from the cell block in thyroid FNA observed in this study made this preparation a useful technique for ancillary studies such as immunohistochemistry and molecular tests. One case was diagnosed as Hurthle cell neoplasm by FNAC and revealed by histopathological examination as Hurthle cell adenoma. High prevalence of undetected thyroid disorders in an iodine sufficient adult south Indian population.

Management strategy involves the integration of information from a variety of possible sources including soliitary, clinical examination, biochemical assessment and a spectrum of additional investigation.

Malignancy in solitary thyroid nodule: A clinicoradiopathological evaluation

In those cases where postoperative HPE was reported as malignant either in frozen or by paraffin section, completion thyroidectomy of the remaining lobe was done. But in cases of carcinoma completion thyroidectomy with adjuvant treatment in the form of radioactive iodine and suppressive therapy.

solitary thyroid nodule thesis

Hemithyroidectomy was followed by thyrlid thyroidectomy in 10 6. In a recent article, the authors have emphasized the role of USG by suggesting that nodules with a nondiagnostic FNAC result in the setting of low-risk demographics and benign appearance at ultrasound can be followed with serial ultrasound examinations, thereby avoiding repeat FNAC.


Malignancy in solitary thyroid nodule: A clinicoradiopathological evaluation

Cytologic evaluation of thyroid nodules. Malignant thyroid sooitary, solitary thyroid nodules, thyroid surgery. The duration of symptoms ranged from one to months. For all patients the following data were recorded: Indian J Endocrinol Metab. J Cancer Res Ther. The incidence of S.

Male gender, normal thyroid volume, single nodularity, nodule hypo echogenicity, size and blurred margins were also associated with malignancy, but thesiw significantly.

Thyroid lobectomy is recommended in patients with recurrent cysts. Histopathological examination of excised specimens showed 28 Patients with thyroid cancer are usually treated with a total thyroidectomy.

solitary thyroid nodule thesis

Decision of neck dissection was taken in those cases with either palpable lymph nodes in the neck or USG finding suggestive of lymphadenopathy. The goal solirary the evaluation of the thyroid nodule is to wolitary and surgically treat patients with malignancies, while identifying and avoiding surgery in those with benign, asymptomatic thyroid nodules.

As for the autonomous toxic nodule, the treatment is either by radioactive iodine or surgical resection. Importance was given to detailed history; duration of swelling, thrsis symptoms, and symptoms associated illnesses, previous exposure to neck irradiation, history of anti-thyroid drug use, positive family history. Oto cli of N Ame. Abstract Thyroid nodules are very common in the general population, while thyroid cancer is relatively uncommon. Sherif, Mahmoud Farouk Mohammed Ali. C is the most important investigation that can distinguish benign from malignant lesions; however it has also some drawbacks such as false negative results and can not differentiate between follicular adenoma and carcinoma.


In five patients scan did not reveal any residual disease. Int J res Med Sci. Accuracy of thyroid FNAC was Immunohistochemical analysis of cell block specimens of colloid nodular goiter 12 cases with CK19 showed absent expression in 11 out of 12 cases The patients and their relatives gave consent to use the information for publication purpose.

Author: Mohamed ,Mohamed Mamdouh,/ Title: Radiological management of solitary thyroid Nodule/

Findings on ultrasonography and ultrasonography predictors of malignancy Ultrasonographic examination findings were available in patients out of clinically detected STN. Many potential molecular markers have been studied to improve the accuracy of FNAB and have shown great promise in their ability to detect malignancy in FNAB specimens particularly those indeterminate or suspicious biopsies. Tthesis are found through physical examination or incidentally through imaging modalities performed for other reasons.

We have noted that male gender, micro calcification, solid echogenicity of the nodule, and presence of cervical lymphadenopathy was significantly associated with malignancy as noted by Tai et al. Solitary thyroid nodules STN have a high likelihood of being malignant.

solitary thyroid nodule thesis

For the cystic nodules, aspiration is both diagnostic and curative, with post aspiration observation.